The Bionano Prep Direct Label and Stain-G2 (DLS-G2) kit offers increased reagent stability and labeling efficiency, according to the company, resulting in a significantly faster sample-to-results workflow. The Bionano Prep SP-G2 kit offers higher gDNA quality, improved ease of use, and increased DNA throughput. According to Bionano, the reports from OGM-Dx HemeOne will include a targeted analysis of guidelines-based, disease-specific SVs, and a whole-genome analysis for the detection of recurrent and novel biomarkers associated with various hematological malignancy indications.īionano Genomics Sample Prep Kits, Chips, and Instrument Softwareīionano Genomics has launched new versions of its sample prep kits, chips, and instrument software. The assay analyzes blood or bone marrow samples to detect structural variants (SVs) of diagnostic and prognostic utility in individuals with a new or an existing diagnosis of a hematological malignancy. According to Thermo Fisher, the kit obtained its CE-IVD mark in May 2022.īionano Laboratories, a subsidiary of Bionano Genomics, has launched OGM-Dx HemeOne, a laboratory-developed test based on optical genome mapping (OGM). The assay works with HIV RNA extracted from plasma or dried blood spots and is designed to detect genomic mutations in the protease, reverse transcriptase, and integrase regions of the HIV-1 pol gene across nine subtypes of global significance. Based on Sanger sequencing, the test examines positive HIV samples to identify genetic variants that may resist common antiretroviral therapeutics. Thermo Fisher Scientific has launched the CE-IVD-marked Applied Biosystems TaqPath Seq HIV-1 Genotyping Kit. Thermo Fisher Scientific Applied Biosystems TaqPath Seq HIV-1 Genotyping Kit Qiagen is touting CLC Genomics Workbench Premium as "ideal" for neonatal screening for hereditary diseases or population genomics studies. The company said that this technology will allow laboratories to process a genome sequenced at 34X depth in 25 minutes for $1 of cloud computing costs and a 50X exome in 90 seconds for a few pennies on "standard" clouds. Qiagen Digital Insights has released an update to its Qiagen CLC Genomics Workbench Premium, incorporating a software accelerator called LightSpeed for faster analysis of next-generation sequencing data. Advances in Clinical Genomics Profiling.Data analysis uncovered 9,594 simplex markers, including 4,523 which permitted the creation of parental genetic maps, and the detection of 7 QTL for grazing resistance of lucerne. Globally, the two tested tools are suitable but the Linux protocol seems more efficient due to its capacity of full automation. Parental and progeny genomes have been sequenced by GBS then analysed with two different methods in order to compare their performances: the use of an adequate software for high-throughput data analysis, CLC Genomics Workbench and the use of an analysis protocol under Linux. Two parents from a Mediterranean productive variety have been crossed with two parents from another variety, grazing tolerant but of low productivity, to conceive four mapping populations. This study focused on lucerne, Medicago sativa, which is a highly heterozygous autotetraploid plant, in order to detect grazing resistance QTL. These molecular markers are numerous in large genomes and facilitate genetic mapping, required to discover Quantitative Trait Loci (QTL) for plant breeding. Genotyping By Sequencing (GBS) is one of these technologies and allows detection of Single Nucleotide Polymorphism markers (SNP). Improvements in high-throughput sequencing technologies currently allow a rapid and cheap sequencing for large and highly diverse genomes.
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